• The concept of metronomic chemotherapy began

  2019-05-10

  

  The concept of metronomic chemotherapy began in the 1990s, when Kerbel showed chemotherapeutic agents may be able to target tumor vessel endothelial cells. In 2000, Browder et al demonstrated a more frequent, lower dose of cyclophosphamide, i.e. anti-angiogenic schedule, could induce response in tum

• According to several cases earlier reported by Gandhi et al

  2019-05-10

  

  According to several cases earlier reported by Gandhi et al, the median time of acute pancreatitis occurring is 12 days (range: 9–16 days), from the last administration of BV, and most events occurred in the first course of BV treatment. One patient experienced recurrent pancreatitis in the fifth co

• Similar to HF myocardial infarction MI is

  2019-05-09

  

  Similar to HF, myocardial infarction (MI) is followed by significant down-regulation of multiple K currents in the peri-infarct zone. These changes may contribute to after-depolarization and ventricular arrhythmia in MI ventricles. However, none of the previous studies reported MI in an increased IK

• After overdrive pacing excitation that is

  2019-05-09

  

  After overdrive pacing, excitation that is one lap behind (the second beat after the stimulus) is caused by several mechanisms. One is the prolonged conduction time that is longer than the TCL due to a long conduction pathway and/or slow conduction. The other is the dual-loop reentry [12]. The excit

• Amongst other anti arrhythmic medications

  2019-05-09

  

  Amongst other anti-arrhythmic medications, disopyramide (class 1A AAM) has anticholinergic side effects such as dry mouth, urinary hesitancy, constipation and exacerbation of conditions like glaucoma and myasthenia gravis. Disopyramide acts by targeting the fast sodium Mifepristone in the cardiac t

• La ignorancia que evidencia Xa Am rica po tica

  2019-05-09

  

  La ignorancia que evidencia Xa. América poética respecto de los literatos mexicanos corrobora la falta de proximidad entre zonas tan distantes del orbe hispanoamericano. Al mismo tiempo comprueba el vacío biográfico que en este punto muestran las revistas mexicanas o, más exactamente, El Recreo de l

• The work by Fumiaki Imamura and colleagues in this issue

  2019-05-09

  

  The work by Fumiaki Imamura and colleagues in this issue of is a unique attempt to evaluate measures of dietary quality and their trends in most countries worldwide. They used a wide range of data sources, including nationally representative dietary surveys, local surveys, and foods disappearance d

• Al concluir las deliberaciones el

  2019-05-09

  

  Al concluir las deliberaciones, el congreso resolvió apoyar las gestiones de los gobiernos de “Argentina, Guatemala, Uruguay, Paraguay, Chile y Bolivia por su valiente postura de no dejarse intimidar, ni por las amenazas difamatorias en su contra, ni por las presiones y amenazas del ‘cartercomunismo

• When the subject of climate change is raised people

  2019-05-09

  

  When the subject of climate change is raised, people tend to think of extreme heat events, droughts, violent storms, rising sea levels, and floods. Today, we certainly live in an era of severe weather events, which will intensify if human-driven climate change continues unabated. Such events are kno

• Interpretation Haitian children have unacceptable rates of

  2019-05-09

  

  Interpretation Haitian children have unacceptable rates of raised blood lead concentrations, with an unexplained disproportionate elevation in children living in the Centre department. Our findings suggest that routine, widespread screening, detailed investigation into modifiable risk factors, targe

• In terms of outcome based assessments

  2019-05-09

  

  In terms of outcome-based assessments, we analyzed the primary outcomes in both the 7-day and in-hospital mortality, to evaluate further whether the cause of death would be related to acute illness or chronic comorbidities, and furthermore to ensure care quality in both units. Illness severity and t

• In the cardiac catheterization room the patient

  2019-05-09

  

  In the cardiac catheterization room, the patient was sedated with propofol. Then, electrode catheters were placed in the coronary sinus from the right subclavian vein, in the right atrial appendage, and in the superior vena cava from the left femoral vein. A pressure line was inserted from the right

• Hereditary syndromes with increased risk for gastric cancer

  2019-05-09

  

  Hereditary syndromes with increased risk for gastric cancer include: 1) hereditary diffuse gastric cancer, 2) Lynch syndrome/hereditary non-polyposis colorectal cancer, 3) juvenile polyposis syndrome, 4) Peutz-Jeghers syndrome and 5) familial adenomatous polyposis. Hereditary diffuse gastric cancer

• EPZ5676 A quadripolar mapping catheter was placed

  2019-05-09

  

  A quadripolar mapping catheter was placed along the RV septum, and a 3.5mm bidirectional open irrigated mapping catheter (ThermoChool SF®, Biosense Webster, Johnson׳s & Johnson׳s, Diamond Bar, CA, US) was inserted retrogradely into the LV. An electroanatomical substrate map created using the CARTO3®

• Based on the close relationship of the canine

  2019-05-08

  

  Based on the close relationship of the canine wedge model to human ECGs, individuals with prominent J waves (ERS) or J/ST elevation (BS) are thought to have accentuated ventricular AP notch and the potential to lose their AP dome because of extrinsic factors such as vagal stimulation, sodium channel

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