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The ability of tumors to progress to more malignant
2019-06-13

The ability of tumors to progress to more malignant phenotypes depends on tumor microenvironment. Blood capillaries, made up of endothelial cells, are usually static under physiological conditions but are induced to proliferate by direct exposure to angiogenic factors, for instance, vascular endothe
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br Management of warfarin during pacemaker implantable cardi
2019-06-13

Management of warfarin during pacemaker/implantable cardioverter defibrillator insertion Until recently, warfarin use was halted before PM/ICD insertion and the patient was bridged with intravenous (IV) unfractionated heparin or subcutaneous low-molecular-weight heparin (LMWH) if the thromboembol
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A meta analysis of seven observational
2019-06-13

A meta-analysis of seven observational studies, comparing dabigatran with warfarin, indicated that the ability of dabigatran to prevent ischemic stroke and bleeding outcomes is comparable to that of warfarin, which is consistent with the data obtained from the RE-LY trial [9]. These findings do not
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Esta simbiosis altamente pol mica en los terrenos de
2019-06-13

Esta simbiosis altamente polémica en los terrenos de la narrativa, el ensayo y la crítica literaria coincidía con lo que unos años atrás había dado Phenyl sulfate conocer: en 1972 apareció un volumen de estudios teóricos en torno del tema del realismo. No se trataba de textos escritos por nuestro au
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Vistos por lo tanto desde la ideolog a
2019-06-13

Vistos, por lo tanto, desde la ideología revolucionaria ascendente, los marginales/campesinos conformaron, más que una presencia ciudadana, en sentido moderno, una especie de sensibilidad motivadora en la que se autorrecreaba una ontología de lo nacional. Esta fuerza fue muy importante en la articul
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Entre estas perspectivas subyace un complejo concepto
2019-06-13

Entre estas perspectivas subyace un complejo concepto de paz que implica una relación dialéctica con la justicia, pues ésta “no consiste únicamente en el pacifismo lpl receptor ultranza o en la ausencia de guerra”. En ello radica el interés profundo de la tl por la esperanza cristiana de una paz efe
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br Discussion Appendicitis is seen in
2019-06-13

Discussion Appendicitis is seen in the general population with a lifetime cumulative incidence rate of 9% [7]. Our calculated incidence rate of appendicitis in the setting of acute leukemia (1.9%) correlates with the reported incidence of 0.5–4.4% [1]. Leukemic involvement of the gastrointestinal
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The number of residents in London who were originally
2019-06-13

The number of residents in London who were originally from the 21 endemic countries in Central and South America was calculated from the 2011 UK National Census and was stratified by borough. We did not include undocumented migrants and individuals born to mothers from endemic Latin American countri
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In patients with syncope episodes detecting type
2019-06-12

In patients with syncope episodes, detecting type 1 ECG (spontaneous or drug-induced) and evaluating the characteristics of symptoms are important for determining the indication for ICD implantation. The result of EPS is supportive; however, it should be noted that VF is not induced during EPS in al
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br Discussion The implant of a CRT
2019-06-12

Discussion The implant of a CRT device in a patient with a resting ejection fraction of 50% represents off-guideline use of this therapy [1]. However, since the patient׳s significant NYHA Class III symptoms, LBBB and exertional ventricular dysfunction achieved evidence-based levels for improvemen
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HRU resulting from SREs is of increasing relevance
2019-06-12

HRU resulting from SREs is of increasing relevance in times of financial and economic restraint because it can help to determine the financial burden to hospital managers and payers. A separate analysis of the costs associated with SREs in this study found that the most costly SRE, spinal cord compr
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Major outcomes from MADIT II trial suggested that
2019-06-12

Major outcomes from MADIT-II trial suggested that, once again, the risk of death in defibrillator group was significantly less than conventional-therapy group with hazard ratio of 0.69. In this trial, the major drawback was corrected. The medication use remained balanced between ICD patients, and co
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br Discussion A previous report demonstrated an adenosine se
2019-06-12

Discussion A previous report demonstrated an adenosine-sensitive reentrant AT not involving an AV nodal pathway in the vicinity of the apex of Koch\'s triangle, which could be ablated at the earliest atrial activation site in the right supero-septal region [3]. Otomo et al. reported a “left-varia
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br Other candidate genes br The frequency
2019-06-12

Other candidate genes The frequency of minor gene mutations in BrS As mentioned above, more than 10 genes have been reported to cause BrS. The proportions of BrS patients who are mutation carriers, however, are very small, except in the case of SCN5A. In a recent extensive mutation analysis of
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cellular metabolism ICE was introduced as a real time imagin
2019-06-12

ICE was introduced as a real-time imaging technique to assist catheter ablation procedures. Chu et al. performed an ICE-guided catheter ablation in 9 dogs. They concluded that ICE can accurately guide catheter ablation directed at anatomic landmarks. They also used ICE to confirm the endocardial con
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