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There are some models of sleep deprivation
2019-04-18
There are some models of sleep deprivation, such as acute or chronic, total or selective sleep deprivation, sleep restriction, or sleep fragmentation. Modifed multiple platform method (MMPM) in our study causes a particularly strong reduction in REM sleep, breaks the sleep continuity. Previous studi
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The tumor microenvironment is enriched with EMVs that are
2019-04-18
The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma
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br Homing of DTCs to the HSC niche The
2019-04-18
Homing of DTCs to the HSC niche The HSC niche is a complex microenvironment comprised of many cell types, including endothelial cells, adipocytes, osteoclasts, osteomacs, and order MM-102 of osteoblastic lineage [5]. A healthy HSC niche provides homing signals to healthy HSCs in order to promote
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br Discussion Studies have reported that permanent PMI using
2019-04-18
3. Discussion Studies have reported that permanent PMI using the conventional pectoral approach is impossible or contraindicated in 1–6% of patients [1–5]. In such patients, PMI via the iliac vein is considered an effective alternative. The advantages of this approach are that the wound size and
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Funding secured by Not applicable
2019-04-17
Funding secured by: Not applicable. Data collection: Sheldon M. Singh, MD, Ramanan Kumareswaran, MD. Conflict of interest Acknowledgments Introduction Early repolarization pattern (ERP) is characterized by an elevation greater than 0.1mV of the junction between the end of the QRS complex
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De manera puntual ambos gobiernos dejaron sentadas sus
2019-04-17
De manera puntual, ambos gobiernos dejaron sentadas sus posiciones ante el nuevo proceso bilateral para normalizar sus relaciones. En su alocución del 17 de diciembre de 2014, el general Raúl Castro destacó, entre otras cosas, que desde su elección como presidente de los consejos de Estado y de Mini
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akt inhibitor Chronic hepatitis B virus HBV infection is
2019-04-17
Chronic akt inhibitor virus (HBV) infection is prevalent in many Asian countries, notwithstanding three decades of universal hepatitis B vaccination programs. The invention of nucleos(t)ide analogs (NUCs) was a breakthrough in the treatment of chronic hepatitis B (CHB). However, HBV continues to be
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br Discussion Primary lymphoma of bone is
2019-04-17
Discussion Primary lymphoma of bone is a rare disease, first described by Oberling in 1928 and he labeled it as reticulum cell sarcoma of bone because of the presence of characteristic reticulin fibers within the lesion [5]. This work was followed by Parker and Jackson and later by Ivin and Bosto
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Our results are consistent with previous findings in
2019-04-17
Our results are consistent with previous findings in other malignancies. Functional assays revealed that ectopic expression of UCA1 promoted cell proliferation and/or reduced cell apoptosis in non-small cell lung cancer [19], breast cancer [18], colorectal cancer [28], and renal cell carcinoma [23].
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Introduction Atrial fibrillation AF is the most common cardi
2019-04-17
Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it commonly occurs after cardiac surgery. AF is often associated with stroke, congestive heart failure, and myocardial infarction, all of which contribute to the increase in the length of hospital stay, higher medical
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Estas ideas permanecieron vigentes durante mucho
2019-04-17
Estas ideas permanecieron vigentes durante mucho tiempo antes de la revolución científica desatada por el racionalismo. Un ejemplo es cómo las nociones neumáticas —derivadas de la idea de que el mundo fue creado por un soplo divino— todavía son palpables en el Primero sueño de sor Juana cuando inici
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br Signal averaged electrocardiography SAECG SAECG
2019-04-16
Signal-averaged electrocardiography (SAECG) SAECG is a high-resolution electrocardiographic technique developed in the 1970s for detecting patients who are prone to SCD after MI. It is based on the theory that lethal ventricular arrhythmias leading to SCD often have a reentrant mechanism. Reentry
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The acute effects of goserelin on
2019-04-16
The acute effects of goserelin on bone have also been evaluated by prospective trials of goserelin+/− adjuvant tamoxifen. The Zoladex in Premenopausal Patients trial randomized 89 women with early breast cancer to goserelin+/− tamoxifen, tamoxifen alone and no endocrine therapy. After 2 years of tre
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br II En lo que sigue proponemos un
2019-04-16
II En lo que sigue, proponemos un análisis de El fistol del diablo que parte inicialmente de una etnografía simbólica de objetos de valor estético —caso ilustrado en la novela de Payno con un fistol de diamante engastado—, con raíces en leyendas y en la historia literaria de varias naciones del m
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buy D-Luciferin When the subject of climate change
2019-04-16
When the subject of climate change is raised, people tend to think of extreme heat events, droughts, violent storms, rising sea levels, and floods. Today, we certainly live in an era of severe weather events, which will intensify if human-driven climate change continues unabated. Such events are kno
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