• Second governments can play an important part in providing

  2019-05-04

  

  Second, governments can play an important part in providing incentives for industry to invest in discovering new uses for old drugs. For example, it eletriptan could consider the extension of patent protection for old drugs that have found new uses, for example, as embodied in the Hatch-Waxman Act

• Two other groups subsequently published

  2019-05-04

  

  Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant

• br Discussion A previous report demonstrated an

  2019-04-30

  

  Discussion A previous report demonstrated an adenosine-sensitive reentrant AT not involving an AV nodal pathway in the vicinity of the apex of Koch\'s triangle, which could be ablated at the earliest atrial activation site in the right supero-septal region [3]. Otomo et al. reported a “left-varia

• br D microCT data Bone

  2019-04-30

  

  3D microCT data Bone volume (BV/TV) ranged from 10.8 to 13.5% consistent with the published literature [18]. Trabecular thickness (Tb.Th), trabecular wst-1 (Tb.Sp), trabecular number (Tb.N) and bone surface per tissue area (BS/TV) values were also consistent with the range published in the liter

• Extra amente el narrador de Rubem Fonseca omite cualquier al

  2019-04-30

  

  Extrañamente, el narrador de Rubem Fonseca omite cualquier alusión rac protein esta segunda carta, quizá considerando él mismo que no es auténtica, mientras que la primera es citada de una forma premonitoria, al igual que las palabras de Papá Miguel: “Deixo à sanha dos meus inimigos o legado da min

• br Results and discussion In this study the np

  2019-04-30

  

  Results and discussion In this study, the np9 and gag mRNA expression was established for 25 patients with CLL (Fig. 1). We found that the transcriptional activity of HERV-K np9 gene in CLL patients was higher than in PBMCs from healthy donors. The results revealed that 18 out of 25 CLL patients

• Funding NIH K AI PATH Gates Foundation

  2019-04-30

  

  Funding NIH K23-AI103105, PATH, Gates Foundation 50274, UW MSRTP, AOA Carolyn Kuckein Fellowship, IDSA Medical Scholars. Declaration of interests Abstract Background Safe, timely and accessible global essential surgery and anaesthesia, once neglected in global health, is now an integral part of

• Automated template matching available in some electrophysiol

  2019-04-30

  

  Automated template matching, available in some electrophysiology systems, has been used to improve pace matching in the ventricle [13]. We found that using automated analysis improved the resolution of pace mapping, especially with bipolar EGMs. The matching algorithms are relatively simple and not

• Understanding and defining these miRNA profiles

  2019-04-30

  

  Understanding and defining these miRNA profiles helps to uncover the clinical usefulness of miRNAs. Numerous human clinical trials are currently evaluating miRNA therapeutics during various liver diseases, such as targeting miR-122 during chronic hepatitis C infection. Aside from therapeutics, the d

• Inhaled corticosteroids long acting agonists and long acting

  2019-04-30

  

  Inhaled corticosteroids, long-acting β-agonists, and long-acting muscarinic agonists are all expensive drugs and many patients in China cannot afford them. An alternative pharmacological treatment for COPD, phosphodiesterase-4 inhibitor, is awaiting approval by the China State Food and Drug Administ

• We would like to also clarify that

  2019-04-30

  

  We would like to also clarify that we do not underestimate the CIs in our study through the assumption that GDP was observed independently for every child in the survey. The multilevel design and clustering of standard errors at the survey level accounts for the fact that GDP is not observed indepe

• Assim pensamos que os discursos analisados neste artigo cons

  2019-04-30

  

  Assim, pensamos que os discursos, analisados neste artigo, construídos pelos intelectuais colaboradores de Araucaria de Chile e difundidos pela revista, ao ressaltarem duas vitoriosas revoluções armadas latino-americanas, exatamente no período de vigência da prpm, dialogaram, de alguma maneira, com

• Ahondando en su querella Nelken sostendr

  2019-04-29

  

  Ahondando en su querella, Nelken sostendrá que nada hay de refinado en el asunto, entre otras cosas porque “copiar deformándola un poco la obra de un pintor de vanguardia es cosa fácil, al alcance de cual-quiera” (1958: s. p.). Sin embargo, su descalificación se torna de nuevo argumento order niclos

• ste se elabor bajo el auspicio de

  2019-04-29

  

  Éste se elaboró bajo el auspicio de la aeu y de las autoridades universitarias, quienes dieron su consentimiento para usar el muro, por lo que fue acompañado con una placa de mármol que da testimonio de este suceso. El grupo Tábano, identificado por su radicalismo dentro de la Universidad, había man

• Why is seasonal litchi encephalopathy a

  2019-04-28

  

  Why is seasonal litchi encephalopathy a relatively recent event in India, Bangladesh, and Vietnam? The most plausible explanation is the rapid expansion of commercial litchi production across Asia and beyond. Indian production is second only to China\'s, from where originates and its potential toxi

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